A case study of a U.K. woman whose lung tumour shrunk without the aid of conventional treatments while she was taking a daily dose of cannabidiol (CBD) oil has scientists suggesting it may be worth studying the use of CBD oil further.
The report,, describes how the woman鈥檚 tumour shrunk from 41 mm to 10 mm in roughly two and a half years.
Cannabinoids are similar to endocannabinoids, which are manufactured by the human body to help in various processes, such as nerve function, energy metabolism, pain and inflammation and immune function, among others.
While cannabinoids have been studied as a primary cancer treatment before, the results have been inconclusive and inconsistent, making it difficult to pinpoint if it actually had any impact.
In this case report, a woman in her 80s was diagnosed with 鈥渘on-small cell鈥 lung cancer in June 2018 after months of a suspicious cough. She was a life-long smoker, smoking roughly 68 packs a year, and had a background of 鈥渕ild chronic obstructive pulmonary disease,鈥 the report stated.
When she was first diagnosed, even though she was a candidate for treatments aimed at curing her cancer, she declined surgery, radiotherapy and other treatments she was offered.
The report offered the patients鈥 perspective, in which she explained that she declined treatment because she had watched her late husband go through the struggle of radiotherapy.
So doctors decided to simply perform regular CT scans to check up on the patient every three to six months.
During these scans over the next couple years, doctors observed that her lung cancer was shrinking. By February 2021, it had reduced by approximately 76 per cent in diameter, which averaged to a 2.4 per cent reduction per month since diagnosis.
In 2019, the shrinking of the tumour piqued doctors鈥 interests, and the patient was brought in to discuss her results.
In this meeting, she revealed that she had been taking CBD oil 鈥渁s an alternative self-treatment for her lung cancer鈥 since August 2018, which she had sourced from outside of the U.K. She was taking 0.5 ml of the CBD oil, two-three times per day.
鈥淭he supplier advised that the main active ingredients of the 鈥楥BD oil鈥 used by this patient were 螖9-tetrahydrocannabinol (THC) at 19.5 [per cent], CBD at 20.05 [per cent] and tetrahydrocannabinolic acid (THCA) at 23.8 [per cent],鈥 the report stated.
She had noticed a reduced appetite since taking the CBD oil, but apart from that, she had no other changes to her prescribed medications, diet or lifestyle 鈥 she was even still smoking one pack of cigarettes a week still, despite being advised to quit.
The endocannabinoid system in humans, which was only identified in the 1990s, is still a mystery in many ways. Although we know it helps to regulate physiological and cognitive processes and manufactured endocannabinoids that 鈥渁ct as neuromodulators,鈥 just how this system can be tapped into with medication and drugs is a growing research avenue.
Cannabis and cannabinoids in general do have proven therapeutic uses, such as assisting with chronic pain, anxiety and sleep disorders, but research into whether cannabinoids could be used as a direct cancer treatment has not yet come up with a clear answer.
If the did play a part in the woman鈥檚 tumour shrinking, doctors aren鈥檛 sure how the active ingredients worked together to achieve this. Previous research into CBD and THC as treatments for cancer have had contradictory results at times, with THC having been shown in some studies to decrease tumour growth, but has been shown to increase cancer cells in other studies.
Doctors also acknowledged that they were unable to confirm the full list of ingredients in the CBD oil this particular patient took.
The patient certainly believe the CBD oil made the difference, and was quoted in the report as being 鈥渙ver the moon鈥 and intending to continue taking the CBD oil 鈥渋ndefinitely.鈥
But one case report does not prove the treatment works 鈥 yet.
鈥淎lthough there appears to be a relationship between the intake of 鈥楥BD oil鈥 and the observed tumour regression, we are unable to conclusively confirm that the tumour regression is due to the patient taking 鈥楥BD oil鈥,鈥 the report stated.
鈥淢ore research is needed to identify the actual mechanism of action, administration pathways, safe dosages, its effects on different types of cancer and any potential adverse side effects when using cannabinoids.鈥
A Canadian man who is trapped in Lebanon with his family says they are anxiously waiting for seats on a flight out of the country, as a barrage of Israeli airstrikes continues.
NDP House leader Peter Julian says there's more his party wants to do in Parliament before the next election, but if the current dysfunction continues it will become a factor in how they vote on a confidence measure.
A teen charged with the murder of another teen on Prince Edward Island last year has pleaded guilty to a lesser charge of manslaughter.
The jury tasked with determining if Canadian musician Jacob Hoggard sexually assaulted a young woman in northeastern Ontario eight years ago began deliberating Friday after nearly two weeks of testimony that saw the singer and his accuser give starkly different accounts of what happened.
A 21-year-old Yazidi woman has been rescued from Gaza where she had been held captive by Hamas for years after being trafficked by ISIS.
Parts of icy Antarctica are turning green with plant life at an alarming rate as the region is gripped by extreme heat events, according to new research, sparking concerns about the changing landscape on this vast continent.
A 21-year-old man who was charged with attempted murder in the shooting of a Toronto police officer this week was out on bail at the time of the alleged offence, court documents obtained by 愛污传媒 Toronto show.
Prosecutors have charged a Michigan man with killing and dismembering a janitor he met on the dating app Grindr.
Nearly 30 years after a six-year-old girl disappeared in Western Arkansas, authorities have identified a suspect in her abduction through DNA evidence.
The owners of a North York condominium say they are facing a $70,000 special assessment to fix their building's parking garage. '$70,000 is a lot of money. It makes me very nervous and stressed out of nowhere for this huge debt to come in,' said Ligeng Guo.
The federal Fisheries Department says it is concerned about a "pattern" of violence and threats toward its enforcement officers after two tense incidents off southwestern Nova Scotia last month.
The owner of a Gatineau, Que. caf茅 says it's 'silly' that Quebec's language watchdog is telling the business to write its Instagram posts in French.
A teen charged with the murder of another teen on Prince Edward Island last year has pleaded guilty to a lesser charge of manslaughter.
NDP House leader Peter Julian says there's more his party wants to do in Parliament before the next election, but if the current dysfunction continues it will become a factor in how they vote on a confidence measure.
More than half of the 205 firearms lost by the Royal Canadian Mounted Police since 2020 have been recovered, but two machine guns remain missing.
The U.S. and British militaries struck more than a dozen Houthi targets in Yemen on Friday, going after weapons systems, bases and other equipment belonging to the Iranian-backed rebels, U.S. officials confirmed.
Armed men belonging to the Gran Grif gang killed at least 70 people, including three infants, as they swept through a Haitian town shooting automatic rifles at residents, a spokesperson for the United Nations' Human Rights Office said on Friday.
Iran鈥檚 supreme leader on Friday praised the country鈥檚 recent missile strike on Israel and said it was ready to do it again if necessary, state TV reported.
Prosecutors have charged a Michigan man with killing and dismembering a janitor he met on the dating app Grindr.
UN peacekeepers are staying in their positions on Lebanon鈥檚 southern border despite Israel鈥檚 request to vacate some areas before it launched its ground operation against Hezbollah militants, the UN peacekeeping chief said Thursday.
An Israeli airstrike on a West Bank cafe that the military said targeted Palestinian militants also killed a family of four, including two young children, relatives told The Associated Press on Friday.
NDP House leader Peter Julian says there's more his party wants to do in Parliament before the next election, but if the current dysfunction continues it will become a factor in how they vote on a confidence measure.
Prime Minister Justin Trudeau is set to announce funding to support French-speaking African countries and initiatives to promote the French language in the Francophonie.
Defence Minister Bill Blair says Israel has the right to defend itself in 'a calibrated and proportional way' following Iran鈥檚 ballistic missile attack against Israel on Tuesday.
When an Ontario doctor refused to sign off on a mammogram for 38-year-old Sidra Lone, the mother of four says she was left with no choice but to lie.
Staff at Saskatoon's Royal University Hospital are calling for systemic changes just two days after its emergency room was more than three times above its capacity.
An Ontario child has died after coming in contact with a rabid bat, a health official confirmed on Wednesday.
For humans, flashing a smile is an easy way to avoid misunderstanding. And, according to a new study, bottlenose dolphins may use a similar tactic while playing with each other.
Alphabet's Google is testing showing check marks next to certain companies on its search results, a company spokesperson said on Friday, in a move aimed at helping users identify verified sources and steer clear of fake websites.
A hacking group tied to Russian intelligence tried to worm its way into the systems of dozens of western think tanks, journalists and former military and intelligence officials, Microsoft and U.S. authorities said Thursday.
The jury tasked with determining if Canadian musician Jacob Hoggard sexually assaulted a young woman in northeastern Ontario eight years ago began deliberating Friday after nearly two weeks of testimony that saw the singer and his accuser give starkly different accounts of what happened.
Legendary singer Paul Simon has said he is 'optimistic' about being able to return to performing live after losing most of his hearing in his left ear.
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Canada's airlines have failed in their challenge of air passenger protection rules that the federal government implemented in 2019.
The Competition Bureau says it's obtained a court order as part of an investigation into potential anti-competitive conduct by the Canadian Real Estate Association.
The Vatican Bank has fired two employees whose recent wedding violates a newly-introduced ban on marriages between staff.
A five-seat sushi counter located inside another restaurant is the latest Vancouver eatery to receive a Michelin star.
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Tesla is recalling more than 27,000 Cybertrucks because the rearview camera image may not activate immediately after shifting into reverse, the fifth recall for the vehicle since it went on sale late last year.
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A group of classic car enthusiasts donated hundreds of blankets to nursing homes in Nova Scotia.
Chantal Kreviazuk is set to return to Winnipeg to mark a major milestone in her illustrious musical career.
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A husband and wife have been on the road trip of a lifetime and have decided to stop in Saskatchewan for the winter.
The grave of a previously unknown Canadian soldier has been identified as a man from Hayfield, Man. who fought in the First World War.
A group of classic car enthusiasts donated hundreds of blankets to nursing homes in Nova Scotia.
Moving into the second week of October, the eastern half of Canada can expect some brisker fall air to break down from the north
What does New Westminster's t蓹m蓹sew虛tx史 Aquatic and Community Centre have in common with a historic 68,000-seat stadium in Beijing, an NFL stadium and the aquatics venue for the Paris Olympics? They've all been named among the world's most beautiful sports venues for 2024.
The last living member of the legendary Vancouver Asahi baseball team, Kaye Kaminishi, died on Saturday, Sept. 28, surrounded by family. He was 102 years old.
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NDP Leader David Eby is vowing to raise British Columbia's speculation and vacancy tax on empty homes if re-elected premier this month.
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Police have arrested a Toronto woman in connection with three recent homicides and investigators say that they believe two of the victims may have been 鈥渞andomly targeted.鈥
A 21-year-old man who was charged with attempted murder in the shooting of a Toronto police officer this week was out on bail at the time of the alleged offence, court documents obtained by 愛污传媒 Toronto show.
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Rural Albertans say they鈥檙e being penalized by high utility fees and some municipalities are asking the government to step in and equalize costs throughout the province.
The owner of a Gatineau, Que. caf茅 says it's 'silly' that Quebec's language watchdog is telling the business to write its Instagram posts in French.
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Saskatoon police arrested a homeless person at the scene of an encampment underneath the University Bridge on Friday morning.
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A northeastern Ontario jury has started deliberating in Canadian musician Jacob Hoggard's sexual assault trial, we can now tell you what they weren't allowed to hear.
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Police in Barrie allegedly seized a semi-automatic pistol and drugs during an overnight investigation that resulted in the arrest of three men downtown.
The Ministry of Labour is investigating a workplace incident that claimed the lives of two people in Georgian Bluffs, south of Owen Sound.
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Brian Masse, Windsor-West鈥檚 Member of Parliament (MP), stood before the House of Commons on Friday, criticizing the eased hazardous material restrictions at the Ambassador Bridge.
NDP Leader David Eby is vowing to raise British Columbia's speculation and vacancy tax on empty homes if re-elected premier this month.
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Archie's Exotic Pet Rescue has been open about six years and, like many other animal rescues, it has seen a surge in surrenders.
It鈥檚 almost deadline day for Lethbridge residents interested in becoming members of one of the city鈥檚 boards, commissions and committees (BCCs).
A northeastern Ontario jury has started deliberating in Canadian musician Jacob Hoggard's sexual assault trial, we can now tell you what they weren't allowed to hear.
A suspect who accused Thunder Bay police of being responsible for his throat injury actually hurt himself when he swallowed a large amount of drugs.
An outfitter in Kenora, Ont., and two individuals have been fined a total of $9,500 for bear hunting offences, including abandoning a bear they shot and using it as bait to hunt another bear.
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A mother in a community where the cost of living is one of the highest in the country says grocery prices are 'inhumane' and retailers are putting profits ahead of people鈥檚 basic human right to food.
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