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Omicron subvariants behind South Africa surge detected in Canada

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Two new Omicron subvariants that are driving a surge of COVID-19 infections in South Africa have been detected in Canada.

In an email to CTVNews.ca, a Public Health Agency of Canada (PHAC) spokesperson confirmed they are aware of three BA.4 cases in Canada, and one of BA.5.

鈥淭he Government of Canada has a strong monitoring program in place with the provinces and territories to identify COVID-19 variants in Canada, including the Omicron variant of concern and its sub-lineages,鈥 they said. 鈥淪cientists are looking for signs that Omicron sub-lineages such as BA.4 and BA.5 change disease severity, transmissibility or impacts the effectiveness of diagnostic tests, vaccines or treatments for COVID-19.鈥

The shows the highly-transmissible BA.2 Omicron subvariant is currently the most common cause of COVID-19 infection in the country.

鈥淎s with all new sub-lineages of COVID-19, scientists from the Public Health Agency of Canada, along with national and international experts, are actively monitoring and evaluating the BA.4 and BA.5 sub-lineages and the associated studies,鈥 the PHAC spokesperson said.

One , which has not been peer-reviewed, suggests BA.4 and BA.5 鈥渟how potential higher transmissibility over BA.2鈥 and could also possibly evade antibodies created from previous Omicron infections.

, also undergoing peer-review, suggests that although vaccination 鈥渨ould likely offer good protection against severe disease,鈥 the two subvariants鈥 ability to dodge antibodies could 鈥渞esult in a new infection wave.鈥

That wave has already started in South Africa, where BA.4 and BA.5 were first identified.

鈥淪ubvariants are driving a major surge in cases,鈥 World Health Organization (WHO) director-general Tedros Adhanom Ghebreyesus said during a . 鈥淥micron, and specifically BA.4 and BA.5, is driving the upsurge in South Africa, while BA.2 is dominant worldwide.鈥

Since late April, new COVID-19 infections in South Africa have numbered in the thousands each day, up from hundreds the month prior. In a , the WHO said there were more than 32,000 cases in the country over the previous week, an increase of 67 per cent. Less than 40 per cent of the population of 60 million is fully vaccinated.

The WHO initially announced it was tracking a few dozen BA.4 and BA.5 cases on April 11. Over the past month, the in countries such as Germany, Portugal, the United Kingdom, Austria, the U.S. and Denmark.

鈥淭he BA.4 and BA.5 subvariants were identified because South Africa is still doing the vital genetic sequencing that many other countries have stopped doing,鈥 Ghebreyesus said earlier in May.

According to the WHO, it鈥檚 too soon to know if BA.4 and BA.5 cause more severe illness.

鈥淚t鈥檚 still very early days with this,鈥 WHO COVID-19 technical lead Maria Van Kerkhove said in . 鈥淲hat we can say at the present time is that it is really critical that people get vaccinated. Vaccines still work incredibly well against preventing severe disease and death.鈥

With files from Reuters and CTVNews.ca Writer Solarina Ho

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